Neural Nexus – Director Change Management

Career Category

Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Neural Nexus – Director Change Management

What you will do

Let’s do this. Let’s change the world. In this vital role of Neural Nexus – Change Management Director will have responsibilities to enable the strategic planning, operational readiness, and comprehensive program management of our organization's innovative Neural Nexus (NN) - Generative AI and Automation platform. The incumbent will drive and deliver the successful design, implementation, rollout, and continuous evolution of this ground-breaking program, ensuring its alignment with cross-functional teams and enterprise priorities to improve business impact.

The individual in this role will not merely lead a technology platform; and will orchestrate a fundamental shift in how Amgen will adopt and harness the power of Neural Nexus and its core components – including Insights Command Center, Adaptive Resource Optimization, and Patient Intelligence Engine.

This position offers a unique opportunity to be at the forefront of AI adoption in a high-impact sector, addressing complex business challenges that merge advanced technology, pharmaceutical data science, and robust governance and agentic frameworks.

Flexible Commuter role to one of two US Sites, in Thousand Oaks, CA, OR Deerfield, IL. You will work on-site a minimum of 3 days a week.

This role is central to enabling Amgen’s AI-driven transformation by embedding change strategy and enterprise readiness into every phase of the Neural Nexus program. The Director will lead high-priority, cross-functional initiatives that ensure successful adoption of AI and automation across the organization, building durable capabilities, reshaping operating models, and driving lasting impact.

Strategic Leadership & Roadmap Development for the NN Platform

• Inspire change planning and execution as part of high-priority, enterprise transformation initiatives under the Neural Nexus umbrella, ensuring alignment between platform roadmap breakthroughs and Amgen’s long-term strategic objectives
• Lead transformation programs or workstreams to deliver business solutions from problem-solving through implementation partnering with Neural Nexus leadership to align organizational change strategies with platform turning points and roadmap objectives, ensuring readiness and adoption are built into long-term planning
• Partner with business and platform leads to assess organizational change impacts and readiness implications of prioritized Automation and Agentic use cases across CD&A, Commercial, Medical, and V&A functions
• Serve as a key enabler of Generative AI adoption by translating complex platform capabilities into clear, actionable business impacts. Engage cross-functional collaborators to develop understanding, manage expectations, and support change readiness within a regulated enterprise environment

End-to-End Management of NN Platform Lifecycle

• Lead the change management strategy across the Neural Nexus platform lifecycle from early planning and business impact assessment through deployment, adoption, and continuous improvement, to ensure organizational readiness at every phase ensuring scalable deployment and sustained business engagement across transformation workstreams
• Develop and manage detailed change workstream plans, timelines, and breakthroughs that align with broader program delivery and enterprise transformation goals
• Collaborate with business unit leads and Neural Nexus partners to assess the organizational change impacts of prioritized use cases, identify affected workflows and teams, and define readiness criteria for successful implementation
• Development & Integration: Partner with the Neural Nexus platform and technology teams to ensure change readiness is integrated into development and deployment plans, aligning operational workflows, communication, and training with evolving solution requirements
• Deployment & Rollout: Plan and complete carefully phased deployment strategies for new Agentic POC and capabilities, leading organizational change effectively and ensuring comprehensive operational readiness for platform adoption across targeted user groups and business processes
• Continuous Improvement & Optimization: Lead the development of processes to continuously assess Neural Nexus adoption, partner feedback, and organizational sentiment. Leverage these insights to identify resistance points, reinforce engagement strategies, and guide iterative enhancements to change plans. Ensure feedback loops are embedded into rollout cycles to support long-term platform relevance, sustained behavior change, and alignment with evolving business needs

Cross-Functional Team Orchestration & Collaboration

• Cultivate a highly collaborative and inclusive environment that breaks down traditional silos, ensuring seamless communication and execution throughout the platform's design, development, deployment, and operational phases
• Serve as a critical liaison to technical AI teams and pharmaceutical domain experts ie. CD&A, Medical, V&A, Commercial, etc. This requires exceptional skill in translating complex technical jargon into understandable business concepts and vice-versa, ensuring mutual understanding, shared objectives, and effective communication protocols across teams with varied backgrounds, priorities, and expertise

Executive Collaborator Management & Strategic Communication

• Partner with executive collaborators to provide change leadership perspective on Neural Nexus adoption and organizational readiness. Serve as a key thought partner in aligning change strategies with enterprise priorities and collaborator expectations
• Develop and deliver change-focused communications and executive updates that convey progress on Neural Nexus adoption, organizational readiness, risks, and performance against key change and engagement metrics. Tailor messaging to align with the needs of diverse business and leadership audiences
• Translate complex Neural Nexus and Generative AI concepts into clear business implications to support change alignment and collaborator understanding. Help lead expectations around GenAI capabilities and limitations in a highly regulated environment using storytelling and value framing to resonate with executive-level audiences and support informed decision-making

Driving Platform Adoption & Value Realization

• Develop and implement comprehensive strategies to drive broad and effective user adoption of the Generative AI platform across the organization, improving the business value derived from its capabilities including the design of fit-for-purpose enablement approaches and monitoring frameworks tailored to functional partner needs
• Inspire change enablement efforts, including collaborator engagement, communications planning, and alignment of training strategies to ensure users are equipped, confident, and motivated to integrate Neural Nexus capabilities into daily workflows
• Define, track, and rigorously report on relevant KPIs to measure platform impact and user engagement, ensuring that the platform supplies to achieving strategic business goals such as accelerated drug discovery timelines, reduced operational costs, or improved quality metrics

Change Management & Continuous Improvement

• Lead and champion change management initiatives associated with the introduction of NN and new automated processes, addressing potential cultural shifts and operational adjustments
• Champion a culture of continuous learning, experimentation (within ethical and regulatory boundaries), and adaptation within the organization, encouraging teams to adopt AI-driven transformation

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a collaborator with these qualifications.

Basic Qualifications:

Doctorate degree and 4 years of Change Management experience

OR

Master’s degree and 8 years of Change Management experience

OR

Bachelor’s degree and 10 years of Change Management experience

In addition to meeting at least one of the above requirements, you must have at least 4 years experience directly managing people and/or leadership experience leading teams, projects, programs, or directing the allocation or resources. Your managerial experience may run concurrently with the required technical experience referenced above

Preferred Qualifications:

• Strong Technical Proficiency (AI/ML): Strong conceptual and practical understanding of AI/ML technologies, with a particular emphasis on Generative AI, model development lifecycles, platform architecture, and the associated data requirements
• Consistent track record of successfully leading large-scale, complex, cross-functional initiatives from conception to completion, including managing executive-level partners in a matrixed organizational structure
• Demonstrable experience in creating strategic roadmaps, handling significant budgets, and allocating resources effectively for technology or operational improvement projects
• Familiar with Biotechnology/Pharmaceutical data and experience working with Medical and/or Commercial field data, reporting, and systems
• Solid understanding of data architecture, data management standard processes, and cloud computing platforms as they pertain to supporting AI/ML workloads
• Passion for deriving data insights, storytelling, and driving measurable impact
• Adaptability and Agility: Demonstrated flexibility and adaptability in a fast-paced, dynamic environment, with the ability to quickly respond to changing market conditions and organizational priorities
• Ethical Standards: A strong commitment to maintaining the highest ethical standards in all analyses and business practices, ensuring unbiased and objective decision-making
• Outstanding exposure to and understanding of AI/ML platform lifecycles, with experience in Generative AI technologies being a strong plus. The ability to grasp both the potential and the limitations of these technologies within a regulated context is crucial
• Demonstrated success in leading organizational change management efforts and driving the adoption of new technologies and processes within a large, complex enterprise
• Experience working effectively with international teams and diverse global collaborators.
• Strategic & Analytical Thinking: Superior ability to analyze complex, dynamic problems, synthesize diverse information streams, develop data-driven strategies, and align operational plans meticulously with overarching business objectives.
• Problem-Solving & Decision Making: Strong, critical problem-solving capabilities characterized by a pragmatic, analytical, and results-oriented approach. Ability to make sound, well-reasoned decisions, often under pressure or in ambiguous situations
• Leadership & Influence: Exceptional leadership capabilities with proven ability to inspire, motivate, and influence cross-functional teams and senior executive partners, often without direct reporting authority. Exhibits strong executive presence and commands credibility
• Communication & Interpersonal Skills: Outstanding verbal, written, and presentation skills. Adept at communicating highly complex technical and strategic concepts clearly, concisely, and persuasively to a wide range of audiences, from technical experts to non-technical executives
• Project & Program Management: Expert-level proficiency in handling complex, wide-ranging projects and programs from initiation through to successful completion. This includes mastery of risk management, resource allocation, timeline management, and dependency tracking
• Discernment: Deep and nuanced understanding of business operations, financial management principles, value creation drivers, and competitive dynamics, particularly within the context of the pharmaceutical industry.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

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Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

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