At Nautilus, we have a big and important mission: improve the health of millions by unleashing the potential of the proteome to accelerate drug development and enable a new world of precision and personalized medicine. We are developing a single-molecule protein analysis platform of unprecedented sensitivity, scale, and ease of use that we believe will democratize access to the proteome – one of the most dynamic and valuable sources of biological insight. To accomplish this, we are pursuing deep, hard science with an entrepreneurial mindset and creating a world-class team of builders, innovators, and dreamers across a wide range of disciplines.
To expand its hardware engineering capabilities, Nautilus is seeking a highly motivated individual with the skills and experience to help bring a complex instrument to the field of proteomics. The successful candidate will collaborate with a cross-functional team of scientists and engineers and play a key role in achieving an exciting and ambitious goal.
Responsibilities
Hands-on design and integration of electronics, electro-mechanical, electro-optic, fluidic and other integrated systems of the Nautilus platform. Support each stage of the development process from prototype through manufacturing handoff and sustaining activities.
Participate in cross-functional project teams with scientists, technical support, and other engineers to create appropriate solutions and resolve hardware, software, and firmware issues.
Collaborate on system design, design reviews, verification and validation testing.
Utilize Product Lifecycle Management tools to maintain design control.
Ensure instrument alignment with guidance documents: IEC61010/IEC60101: including EMC/EMI concerns, RoHS compliance and laser safety.
Conduct board schematics / layout designs (both analog and digital) and associated cable harnesses. Rapidly prototype and qualify new designs. Troubleshoot and verify electronics packaged within tight physical constraints; develop firmware drivers and control software.
Use CAD & EDA software (preference for Solidworks and Altium Designer)
Liaison with outside vendor relationships for manufacturing.
Develop subsystem and system level test strategy; responsible for a broad range of instrument testing, including evaluation of electro-mechanical, fluidic, thermal, and optical subsystems through all phases of development and commercialization.
Hardware design and coding/scripting of controls for feasibility, characterization, design verification, reliability, lifetime, manufacturing, and service test fixtures
Requirements
B.S. or M.S. in Electrical Engineering (or an equivalent technical discipline).
A minimum 4-8 years of experience in hands-on design.
Prior experience with scientific or medical instrument design, preferred.
Cross-functional engineering experience required.
Strong verbal and written communication skills.
Software experience in C and Python preferred.
Hands-on lab skills with shop and test equipment, soldering, breadboarding, prototyping, etc.
Familiar with designs involving motor controls, sensors, pumps, valves, lasers, power, communication, and microcontrollers.
Knowledge of common board level electrical bus standards is preferred.
Experience/ familiarity with microcontrollers.
Exposure to product development/commercialization and test experience within a risk-control framework is strongly preferred.
Fast learner, self-motivated, adaptable and willing to take on evolving responsibilities as needed.
Demonstrated analytical skills and experimental problem-solving skills to understand hardware and software issues and to be able to quickly analyze and resolve system inter-operability problems.
Demonstrated expertise in Altium, Solidworks, or other similar EDA/CAD design tools.
Ability to work well under pressure, handle multiple projects, and meet deadlines.
Nautilus Team Culture
We are curious go-getters: this is a team of life-long learners who aren’t afraid to tackle the big challenges and we embrace the journey.
We are detail oriented: we do great science by working smart & with diligence where we learn from our trials and mistakes.
We are easy to work with: we want our workplace to be one where everyone can share their perspective and be treated with respect and kindness.
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Born from the founders’ recognition that their diverse but complementary skills and experiences would enable them to successfully address challenges that others had not, the company set about solving a vexing problem: how to bring true proteomics ...
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