Let’s get started
By clicking ‘Next’, I agree to the Terms of Service
and Privacy Policy, and consent to receive emails from Rise
Jobs / Job page
Senior Scientist, Analytical Sciences image - Rise Careers
Job details

Senior Scientist, Analytical Sciences

We are looking for a collaborative and technical Senior Scientist experienced in cell culture, immunological techniques, multi-parametric flow cytometry and cell-based functional assays as part of bioassay development. You will deliver new/optimized analytical methods and evaluate new analytical technologies. You will be responsible to develop cell-based analytical methods aligned with vector and cellular therapy product CQAs to enable process development, product characterization, stability and release testing of novel engineered cell therapy products. The Senior Scientist will work with the Process Development and Quality Control teams. This role is based in Santa Monica, CA and reports directly to the Director, Product Analytical Sciences.

You Will:

  • Provide strategic, technical, and scientific leadership to a technical analytical method development team, assign tasks, review data, and strengthen regulatory concepts (cGMP).

  • Advance and implement cell-based bioassay/potency (e.g. cytotoxicity, proliferation, cytokine production) and immunophenotyping by multi-parametric flow cytometry methods from conception through optimization, qualification, and method transfer to Quality Control and external partners as part of an analytical control strategy and to support Process Development.

  • Employ quality by design (QbD) and design of experiment (DOE) approaches to method development to quickly identify robust operating regions within phase-appropriate pre-defined acceptance criteria aimed to meet ICH guidelines.

  • Work with Process Development, completing and documenting analytical methods as part of experimental study plans to progress and characterize novel engineered cell therapy platforms, and occasionally perform routine assays for characterization.

  • Work with Quality partners during technology transfers, help draft qualification/validation protocols/reports.

  • Write, review and edit accurate technical and development reports, CMC sections for regulatory submissions, and SOP/maintenance/user requirements for relevant equipment

  • Participate in group and department meetings, present scientific data, provide expertise in areas of responsibility.

  • Maintain, calibrate and operate analytical equipment and instrumentation that is used routinely in execution of assays.

You Have:

  • 7+ years with BS/BA; 5+ years with MS/MA; 2+ years with PhD in Immunology, Oncology, Cell Biology, or related discipline

  • Demonstrate knowledge of Process Development of cellular therapy products and Analytical Method Development within a regulated environment

  • First-hand experience in development and qualification of immunoassays, multi-parameter flow cytometry, and cell-based potency methods for release in a QC/regulated environment

  • Demonstrate advanced knowledge in T cell biology and cell signaling pathways

  • Excellent skills in Microsoft Excel, and Powerpoint and data analysis software (e.g. Prism, JMP, FlowJo, CytEpert, SoftMax Pro)

  • Ability to think critically and demonstrate troubleshooting and problem solving skills.

  • Willing to accept temporary responsibilities outside of initial job description.

The annual base salary for this position ranges from $108,473 to $162,710. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).

Our Benefits:

Benefits offered include:

  • A qualified retirement program [401(k) plan]

  • Paid vacation, holidays, and paid leaves

  • Health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

#celltherapy #LI-Onsite

Date Posted

12-Jun-2025

Closing Date

25-Jun-2025Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.
AstraZeneca Glassdoor Company Review
4.1 Glassdoor star iconGlassdoor star iconGlassdoor star iconGlassdoor star icon Glassdoor star icon
AstraZeneca DE&I Review
No rating Glassdoor star iconGlassdoor star iconGlassdoor star iconGlassdoor star iconGlassdoor star icon
CEO of AstraZeneca
AstraZeneca CEO photo
Pascal Soriot
Approve of CEO

Average salary estimate

$135591.5 / YEARLY (est.)
min
max
$108473K
$162710K

If an employer mentions a salary or salary range on their job, we display it as an "Employer Estimate". If a job has no salary data, Rise displays an estimate if available.

Similar Jobs
Photo of the Rise User

Lead strategic initiatives in Oncology at AstraZeneca as the Associate Director, Oncology Regional Accounts, driving impactful relationships and healthcare solutions.

Photo of the Rise User
Posted 11 days ago

AstraZeneca is looking for a skilled Global Development Medical Director to drive the innovative clinical research in cardiovascular and metabolic diseases.

Photo of the Rise User
Posted 5 days ago

Be a part of Alcon's mission to enhance eye care as a Sr. Principal in Patient Safety & Experience, driving safety strategies and innovations.

Photo of the Rise User

Become an integral part of AbbVie's mission to innovate in healthcare as an Associate Director focusing on HEOR strategies for Parkinson's Disease.

Photo of the Rise User

Join Eurofins Scientific as a VOA GC chemist, where you will contribute to environmental safety through analytical testing.

Photo of the Rise User
Eurofins Hybrid Barberton, OH, USA
Posted 16 hours ago

Eurofins Scientific is seeking a Laboratory Manager in Barberton, OH to provide technical leadership, manage projects, and ensure high-quality laboratory operations.

Photo of the Rise User
Medtronic Hybrid Minneapolis, Minnesota, United States of America
Posted 2 days ago

Medtronic is hiring a Senior Clinical Research Specialist in Minneapolis to lead clinical study execution and support medical innovation with onsite collaboration.

Join Mirror Physics as an AI Researcher to drive advancements in physics-based simulation and contribute to revolutionary scientific discoveries.

Photo of the Rise User

Become a key player in ensuring environmental safety as a Senior Technical Analyst at Eurofins in Tacoma, WA.

Photo of the Rise User
Posted 10 days ago

Join AbbVie as an Associate Scientist II in Toxicology, where you'll play a key role in pioneering innovative cell culture methodologies.

Photo of the Rise User

Become a vital part of AbbVie’s Ophthalmology Discovery Research as a Postdoctoral Fellow, focusing on innovations in ocular disease.

Photo of the Rise User
Posted 4 days ago

Join Generate:Biomedicines as a Senior Scientist II, where you'll shape innovative therapeutic solutions through computational protein design.

Photo of the Rise User
Posted 18 hours ago

Drive transformative innovation at Philips as the R&D Transducers Leader, leading global teams to pioneer ultrasound transducer development and deliver cutting-edge health technology products.

Photo of the Rise User

Join AbbVie as a Senior Scientist II to drive peptide therapeutic innovations within the Immunology Discovery organization.

Photo of the Rise User
Posted 2 days ago

Technical Targeting Analyst role at Peraton focusing on advanced intelligence analysis and counterintelligence support for national security missions.

AstraZeneca is one of the world’s most exciting bio-pharmaceutical companies. From scientists to sales, lab techs to legal we’re on a mission to turn ideas into life-changing medicines that improve patients’ lives and benefit society. We’re consta...

280 jobs
MATCH
Calculating your matching score...
FUNDING
SENIORITY LEVEL REQUIREMENT
TEAM SIZE
EMPLOYMENT TYPE
Full-time, onsite
DATE POSTED
June 14, 2025

Subscribe to Rise newsletter

Risa star 🔮 Hi, I'm Risa! Your AI
Career Copilot
Want to see a list of jobs tailored to
you, just ask me below!