Senior Director, Data Science

Company Summary: Korro is a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases using its proprietary RNA editing platform. Korro is generating a portfolio of differentiated programs that are designed to harness the body’s natural RNA editing process to effect a precise yet transient single base edit. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability. Using an oligonucleotide-based approach, Korro expects to bring its medicines to patients by leveraging its proprietary platform with precedented delivery modalities, manufacturing know-how, and established regulatory pathways of approved oligonucleotide drugs. Korro’s lead program is Alpha-1 Antitrypsin Deficiency (AATD). Korro is based in Cambridge, Massachusetts.

We are collaborative and united by a common mission. We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases. Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization. They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work. Join us as we redefine what's possible in genetic medicine and work to make a lasting impact on human health.

Position Summary:  

Korro Bio is seeking a dynamic, innovative, and experienced Sr. Director to lead our Data Science team. This individual will provide both strategic direction and hands-on leadership, overseeing the development and execution of Korro’s bioinformatics strategy. A key focus will be enabling efficient data management, analysis, and visualization to support discovery research efforts.

The ideal candidate will bring deep expertise in computational biology and a strong track record in scientific leadership. Success in this role requires the ability to thrive in a fast-paced, interdisciplinary startup environment and a proactive, collaborative mindset.

This position reports to the SVP of Platform Development.

• Function as a key member of Korro Bio’s scientific leadership team, providing scientific expertise, strategic planning, and goal-oriented execution.
• Lead and mentor a small team of data scientists and computational engineers.
• Partner with other groups (e.g. chemistry, platform biology, pharmacology) within research and development to facilitate lead identification, optimization and development candidate nomination.
• Build strong relationships enabling trust, respect and effective collaboration cross disciplinary colleagues to ensure productive and successful company-wide research and development programs.
• Serve as a role model and foster a scientifically rigorous, open and supportive corporate environment.
• Effectively communicate scientific planning, progress and results to Korro’s executive leadership, R&D teams, and external audiences. Additionally, build and develop appropriate relationships with key opinion leaders and SAB members.   

• Ph.D. in a quantitative discipline (Bioinformatics, Statistics, Applied Mathematics, Computer Science, Biophysics, Computational Biology, Physics, Engineering, or Machine Learning) with relevant industry experience, OR M.S. degree with 10+ years of extensive industry experience.
• Minimum 7+ years of industry experience with demonstrated leadership and management capabilities, including proven ability to build, develop, and mentor high-performing teams
• Experience analyzing gene therapy, gene editing, in vitro/vivo assay, genetics, genomics and cell biology data
• Experience analyzing the multiple facets of next generation sequencing data, including amplicon sequencing, tag counting, exon sequencing.
• Experience using comparative genomics as a tool for gene discovery.
• Passionate scientific leader with strong emotional intelligence and exceptional communication skills, adept at navigating a fast-paced, rapidly evolving biotech environment and driving programs forward under aggressive timelines.
• Hands-on approach with meticulous attention to detail.
• Track record of collaboration, stakeholder relationship management, and influencing key decision makers.

Benefits:  Korro offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance, a dependent care flexible spending account and a Company-funded health savings account and free parking.