Senior Scientist II, Protein Biochemistry

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas – immunology, oncology, neuroscience, and eye care – and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

AbbVie is looking for talented Protein Biochemists with strong Protein Sciences expertise to join our team at our headquarters in the Chicago area. This exciting role is central to advancing small molecule drug discovery across a variety of disease areas using innovative biochemical strategies. As an integral member of our team, you will drive projects and collaborate across functions to develop robust and scalable protein workflows and address strategic questions in support of key drug discovery activities, including assay development, screening, structure-based design, and exploratory biology.

Success in this position requires a solid foundation and proven track record in Protein biochemistry and related fields, good understanding and applications of computational protein design tools, and strong collaborative skills.

Key Responsibilities:

• Innovate and lead experimental plans to address essential questions about protein functions and overcome challenges in generating protein /protein complexes with low yield, aggregation issues.
• Enhance and implement best practices in protein expression, purification, and characterization to support drug discovery programs.
• Design complex protein constructs and guide purification processes to enable cutting-edge biochemical/biophysical assays and structural biology research.
• Serve as the technical expert in protein production, utilizing advanced chromatographic techniques on AKTA systems.
• Effectively use of advanced computational tools and the development of novel approaches to strengthen our program capabilities.
• Work closely with project teams to identify and solve key questions within the domain of protein biochemistry.
• Stay ahead of scientific discoveries to integrate valuable insights into evolving protein engineering strategies.
• Lead cross-functional teams, driving biochemistry-focused initiatives that enhance program success.

• Bachelor’s Degree or equivalent education and typically, 12 years of experience, Master’s Degree or equivalent education and typically 10 years of experience, PhD and typically 4 years of experience.
• Demonstrated expertise in producing high-quality proteins and tackling complex challenges.
• Proficiency in programming and the application of bioinformatics tools and computational biology technologies is a plus.
• Comprehensive understanding of the best practices in the field of membrane protein is advantageous.
• Solid experience with nanobody generation technologies.
• Exceptional organizational and time-management skills, with an independent and detail-oriented approach to problem-solving.
• Strong project management skills, capable of leading and contributing to multiple simultaneous projects.
• Excellent collaborative and communication skills, adaptable to both computational and non-computational scientific audiences.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our short-term incentive programs. ​

• This job is eligible to participate in our long-term incentive programs​

​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html