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Director, Computational Chemistry

Job Description

We are seeking a talented, collaborative, and highly motivated individual who has experienced in Computational Chemistry. This role involves working closely with a multidisciplinary research team to discover new small molecules for cancer treatments.

What You’ll Do:

  • Build state-of-the-art drug design methods using computers
  • Design new drug candidates using computational chemistry, cheminformatics, and AI tools
  • Search and development of new AI and IT tools that can be used for drug discovery
  • Collaborate with core team members to advance projects
  • Identify and validate novel drug targets using computational methods
  • Define project objectives and strategy with the supervisor.
  • Interact with cutting-edge researchers from all over the world
  • Mentor a team of scientists for their SBDD skill up
  • Contribute to a culture of collaboration and shared mission

Qualifications

  • Practical experience in various CAD-related drug discovery research or related field with 8+ years in Pharmaceutical biotechs or companies.
  • Docking, Virtual Screening, Molecular Simulation, Homology Modeling, Molecular Dynamics (MD) Computation, Quantum Mechanics, QSAR, Machine Learning, Deep Learning, Chemoinformatics, Ligand-Based and Structure-Based Compound Design, Compound Library Design skills.
  • Programming (Python, R, Pipeline Pilot, etc.) skills, database-related knowledge, and experience.
  • Experience using data analysis software (Spotfire, Tableau, etc.)
    Computational chemistry software or script development skills.
  • Experience working in a matrixed environment and cross-functional drug discovery fields.
  • Flexibility to work on multiple research programs simultaneously.
  • Strong communication and presentation skills.
  • Excellent publication record in peer-reviewed journals.
  • Highly motivated and can take action to take on new challenges.

Additional Information

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $190,000.00 - $260,000.00. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.​

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable).

Benefits:

  • Competitive salary and annual bonus.
  • Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
  • Generous parental leave and family planning benefits.
  • Outstanding culture and opportunities for personal and professional growth.

Apply Now: Join us in our mission to improve the lives of people with cancer. Apply today to become a part of our dynamic team!

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially.  We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.

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Average salary estimate

$225000 / YEARLY (est.)
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$190000K
$260000K

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Passion. Commitment. Culture. At Deciphera, we are committed to improving the lives of people living with cancer. That passion for making a difference extends to the patient groups and communities in which we live and work. We recognize the value...

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Full-time, hybrid
DATE POSTED
June 8, 2025

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